Services
Services
Active Cells Biotechnology boasts a strong track record in R&D within the field of biotechnology, offering contract research services across various application sectors.
What sets Active Cells Biotechnology apart is its flexibility in tackling diverse projects, with comprehensive process development capabilities, from strain isolation to R&D process development and product characterization through to industrialization.
We provide complete technological development programs, ensuring customization and support throughout all project phases.
Our aim is to expand and enhance relationships with partners interested in developing new biocatalysis-based products and processes.
Isolation and Microorganism Characterization
- Isolation and selection of microbial strains
- Phenotypic and genotypic characterization
- Studies on synthesis and degradation metabolism
Strain improvement
- Enhancing strain performance
- Optimizing growth medium and conditions
- Mutagenesis and engineering
- Screening and selection of high-yield variants
- Overcoming inhibitions and resolving operational limitations
R&D process development
- Development and optimization of biotechnological processes in Upstream and Downstream
- Multifactorial matrix studies based on Design of Experiment (DOE) logic
- Development and optimization of fermentation parameters
- Study of product purification and isolation processes
Scale-up e Technology transfer
- Scaling up and industrializing the process
- Determining risk levels and investment costs; transferring to industrial equipment and technologies
- Supporting tech transfers to in-house or external facilitie
Scale down
- Scale-down studies to optimize or modify existing processes
- Improving and adapting production parameters
Biotransformation
- Biotransformation studies using microbial, enzymatic, and chemo-enzymatic catalysis
- Developing biocatalysis processes for pharmaceutical intermediate production
- Replacing chemical steps with sustainable enzymatic approaches
- Optimizing and customizing biotransformation parameters
Downstream and Product Characterization
- Developing product purification processes using technologies like Tangential Flow Filtration (TFF) and Chromatography
- Analytical characterization of the product and impurities
- Developing and validating methods